Vaccines

Vaccine research at the IHR focuses on three areas of importance to the public, Kaiser Permanente members, and policymakers: safety, hesitancy, and delivery. Since 2000, we have partnered with the Centers for Disease Control and Prevention on a national, multi-site project called the Vaccine Safety Datalink (VSD). The VSD project studies the safety of all vaccines currently licensed for use in the US. Our research group also designs, conducts and implements behavioral interventions designed to reduce vaccination concerns and improve vaccine acceptance among parents. Finally, our research group studies methods to increase vaccination coverage rates.


Vaccine Researchers


Featured Projects

Investigators: Jason Glanz, PhD and Matthew F. Daley, MD
The goal of this project is to evaluate the safety of currently licensed (or authorized for emergency use) vaccines in the United States. To accomplish this, we lead specific vaccine safety studies, and use privacy-protecting approaches to contribute electronic health record data to multiple vaccine safety investigations.
Funder: Centers for Disease Control and Prevention
Study End Date: 09/27/2027
Investigators: Jason Glanz, PhD and Matthew F. Daley, MD
The goal of this project is to conduct safety surveillance monitoring of COVID-19 vaccines across 8 integrated health care sites of the Vaccine Safety Datalink.
Funder: Centers for Disease Control & Prevention
Study End Date: 01/06/2026
Investigators: Jason Glanz, PhD and Matthew F. Daley, MD
The goal of this project is to use annual National Immunization Survey-Child data to examine patterns and trends of childhood vaccination patterns across the US and determine whether trends in schedule adherence or completion of vaccine series are modified by rurality.
Funder: National Institutes of Health
Study End Date: 08/31/2025
Investigator: Matthew F. Daley, MD
The goal of this project is to use surveys and electronic health data to find out more about when and where people receive their influenza vaccines to improve the ability of the Centers for Disease Control and Prevention to monitor national influenza vaccination rates. This work is done through the Vaccine Safety Datalink (VSD), a collaborative project between the Centers for Disease Control and Prevention, and 8 health care organizations across the country. The VSD conducts vaccine safety studies based on questions and concerns from the medical, scientific, and public communities. We are starting our 3rd year of surveys in the VSD. In 2021, we are surveying women across the United States who are currently pregnant or were pregnant during the influenza season. We are also asking several questions about the COVID vaccine, such as willingness to get a vaccine when available.
Funder: Centers for Disease Control and Prevention
Study End Date: 03/19/2022
Investigators: Jason Glanz, PhD and Matthew F. Daley, MD
The objective of this project was to develop the infrastructure to supplement existing epidemiologic data with patient-reported information on under-vaccination and the use of alternative vaccination schedules.
Funder: Centers for Disease Control and Prevention
Study End Date: 09/24/2020
Investigator: Jason Glanz, PhD
The objective of this study was to develop and test a vaccine tailored messaging intervention for parents.
Funder: National Institute of Child Health & Human Development
Study End Date: 03/31/2019
Investigators: Jason Glanz, PhD, Debra P. Ritzwoller, PhD, and Matthew F. Daley, MD
Funder: Agency for Healthcare Research and Quality
Study End Date: 07/31/2017