Matthew F. Daley, MD

Senior Clinician Investigator

Matthew F. Daley, MD, is a Senior Clinician Investigator at the Institute for Health Research. He conducts research on a broad range of pediatric-oriented topics. He is focused particularly on vaccine-related topics, including vaccine safety, vaccination coverage, and parental vaccine hesitancy. For many years, he has also worked to expand the use of multi-institutional electronic health record data for public health surveillance and research purposes.

Dr. Daley received his medical training at Stanford University School of Medicine and completed a residency and chief residency in Pediatrics at the University of Colorado.

Dr. Daley is a practicing pediatrician at Kaiser Permanente Colorado, and an Associate Professor in the Department of Pediatrics at the University of Colorado School of Medicine. He is a Fellow in the American Academy of Pediatrics and a member of the Academic Pediatrics Association. He is currently a member of the Advisory Committee on Immunization Practices (ACIP), which provides advice and guidance to the Centers for Disease Control and Prevention (CDC) on the use of vaccines in the U.S. civilian population.

Selected Research:

  • Vaccine Safety Datalink Project
  • The goal of this project is to evaluate the safety of currently licensed vaccines (or authorized, in the case of COVID-19 vaccines) in the U.S. To accomplish this, we lead specific vaccine safety studies, and use privacy-protecting approaches to contribute electronic health record data to multiple vaccine safety investigations.

    • Funder: Centers for Disease Control and Prevention
    • Award End Date: 09/27/2022

  • Vaccine Safety Datalink Assessment of Influenza Vaccination Status
  • The goal of this project is to assess through survey the accuracy of existing influenza vaccination data among adults and pregnant women, to improve the ability of the Centers for Disease Control and Prevention to monitor national influenza vaccination rates.

    • Funder: Centers for Disease Control and Prevention
    • Award End Date: 03/19/2022

  • Vaccine Safety Datalink Infrastructure for Studying the Safety of the Immunization Schedule
  • The objective of this project was to develop the infrastructure to supplement existing epidemiologic data with patient-reported information on under-vaccination and the use of alternative vaccination schedules.

    • Funder: Centers for Disease Control and Prevention
    • Award End Date: 09/24/2020

  • Medications and Weight Gain in PCORnet: The MedWeight Study
  • The objective of this study is to determine the comparative effects of initiating and more sustained exposure to commonly used medications on weight gain and other metabolic outcomes up to 10.5 years after initiation, among children and adults.

    • Funder: National Institutes of Health/NIDDK
    • Award End Date: 01/31/2024

  • Childhood Obesity Data Initiative (CODI)
  • The objective of the CODI project was to develop and implement a reusable system of data integration across multiple sectors focused on childhood obesity and prevention. The CODI project included health care organizations and entities providing healthy weight related interventions, with the goal of providing an integrated, de-duplicated, longitudinal record of care for individuals across organizations, to be used for research and public health surveillance purposes.

    • Funder: Public Health Informatics Institute
    • Award End Date: 09/19/2020