Addiction Health Services / Overdose Prevention
We conduct scientific, epidemiologic, and intervention research to improve the delivery and safety of care for Kaiser Permanente Colorado patients and the broader community affected by addiction. Our work focuses on developing and evaluating approaches that expand access to high‑quality, patient‑centered treatment for substance use disorders, including novel strategies to identify and engage individuals in effective services across diverse settings. We also study ways to improve the safety of opioid prescribing and develop, test, and implement effective strategies to prevent overdoses from pharmaceutical opioids, heroin, fentanyl, and other drugs. Across all efforts, our patient‑centered approaches emphasize practical ways individuals and families can protect themselves from overdose and receive the care they need.
The IHR leads or participates in a number of national research collaborations. These partnerships enable the IHR to contribute to large, cutting edge, multi-site research projects.
- Integrating Addiction Research in Health Systems: The Addiction Research Network (participating research site)
- Developing a Prescription Opioid Registry across Diverse Health Systems (NIH HEAL Initiative)
- Medical Cannabis Use among Primary Care Patients: Using Electronic Health Records to Study Large Population
- Patient and System-Level Factors Associated with HEDIS AOD-IET Measure Performance across Health Systems
Addiction Health Services/Overdose Prevention Researchers
Featured Projects
Investigator: Ingrid A. Binswanger, MD, MPH, MS
This project is an office-based Methadone versus Buprenorphine randomized pragmatic hybrid effectiveness/implementation trial to address retention in medication for opioid use disorder treatment.
Funder: National Drug Abuse Clinical Trials Network, National Institute on Drug Abuse, NIH
Study End Date: 02/28/2028
This project is an office-based Methadone versus Buprenorphine randomized pragmatic hybrid effectiveness/implementation trial to address retention in medication for opioid use disorder treatment.
Funder: National Drug Abuse Clinical Trials Network, National Institute on Drug Abuse, NIH
Study End Date: 02/28/2028
Investigator: Ingrid A. Binswanger, MD, MPH, MS
This project brings together 16 Health Care Systems Research Network member health systems to conduct research focused on all aspects of addiction.
Funder: National Institute on Drug Abuse
Study End Date: 02/28/2025
This project brings together 16 Health Care Systems Research Network member health systems to conduct research focused on all aspects of addiction.
Funder: National Institute on Drug Abuse
Study End Date: 02/28/2025
Investigators: Ingrid A. Binswanger, MD, MPH, MS, Jason Glanz, PhD and Anh P. Nguyen, PhD
This multi-site cohort study of patients receiving medication-based treatment for opioid use disorder across four health systems in the Health Systems Node of the Clinical Trials Network seeks to link electronic health records with novel data to examine health insurance instability and its association with all-cause and overdose mortality.
Funder: National Institute on Drug Abuse’s Clinical Trials Network
Study End Date: 09/30/2024
This multi-site cohort study of patients receiving medication-based treatment for opioid use disorder across four health systems in the Health Systems Node of the Clinical Trials Network seeks to link electronic health records with novel data to examine health insurance instability and its association with all-cause and overdose mortality.
Funder: National Institute on Drug Abuse’s Clinical Trials Network
Study End Date: 09/30/2024
Investigators: Ingrid A. Binswanger, MD, MPH, MS and Jason Glanz, PhD
The major goal of this project is to conduct a longitudinal cohort study to determine the effectiveness and safety of opioid tapering in three large health systems in two states.
Funder: National Institute on Drug Abuse
Study End Date: 12/31/2023
The major goal of this project is to conduct a longitudinal cohort study to determine the effectiveness and safety of opioid tapering in three large health systems in two states.
Funder: National Institute on Drug Abuse
Study End Date: 12/31/2023
Investigator: Ingrid A. Binswanger, MD, MPH, MS
The purpose of this study is to use a prescription opioid registry containing EHR data across nine diverse health systems to assess how different lengths of buprenorphine retention are related to mortality.
Funder: National Institute on Drug Abuse
Study End Date: 05/31/2021
The purpose of this study is to use a prescription opioid registry containing EHR data across nine diverse health systems to assess how different lengths of buprenorphine retention are related to mortality.
Funder: National Institute on Drug Abuse
Study End Date: 05/31/2021
Investigator: Ingrid A. Binswanger, MD, MPH, MS
This study explored ways to improve justice-involved veterans' access to and use of pharmacotherapy for opioid use disorder through qualitative interviews with veterans, VA justice outreach staff, criminal justice system staff, and VA and community health care providers who work with justice-involved veterans.
Funder: National Institute on Drug Abuse
Study End Date: 02/28/2020
This study explored ways to improve justice-involved veterans' access to and use of pharmacotherapy for opioid use disorder through qualitative interviews with veterans, VA justice outreach staff, criminal justice system staff, and VA and community health care providers who work with justice-involved veterans.
Funder: National Institute on Drug Abuse
Study End Date: 02/28/2020
Investigator: Ingrid A. Binswanger, MD, MPH, MS
The objective of this study was to understand the pregnancy desires and motivations of women in opioid medication-assisted treatment and develop and assess the acceptability, feasibility, and initial efficacy of a brief theory-based peer-led intervention to prevent unintended pregnancies among women in treatment.
Funder: National Institutes of Health
Study End Date: 05/31/2019
The objective of this study was to understand the pregnancy desires and motivations of women in opioid medication-assisted treatment and develop and assess the acceptability, feasibility, and initial efficacy of a brief theory-based peer-led intervention to prevent unintended pregnancies among women in treatment.
Funder: National Institutes of Health
Study End Date: 05/31/2019
Investigator: Ingrid A. Binswanger, MD, MPH, MS
This project is an office-based Methadone versus Buprenorphine randomized pragmatic hybrid effectiveness/implementation trial to address retention in medication for opioid use disorder treatment.
Funder: National Drug Abuse Clinical Trials Network, National Institute on Drug Abuse, NIH
Study End Date: 02/28/2028
This project is an office-based Methadone versus Buprenorphine randomized pragmatic hybrid effectiveness/implementation trial to address retention in medication for opioid use disorder treatment.
Funder: National Drug Abuse Clinical Trials Network, National Institute on Drug Abuse, NIH
Study End Date: 02/28/2028
Investigators: Ingrid A. Binswanger, MD, MPH, MS and Jason Glanz, PhD
This study examines the impact and safety of expanded access to naloxone, an effective opioid antidote which reverses opioid overdose, for patients prescribed opioids for pain in two large and diverse health systems.
Funder: National Institute on Drug Abuse
Study End Date: 04/30/2022
This study examines the impact and safety of expanded access to naloxone, an effective opioid antidote which reverses opioid overdose, for patients prescribed opioids for pain in two large and diverse health systems.
Funder: National Institute on Drug Abuse
Study End Date: 04/30/2022
Investigators: Ingrid A. Binswanger, MD, MPH, MS and Jason Glanz, PhD
The major goal of this project is to conduct a longitudinal cohort study to determine the effectiveness and safety of opioid tapering in three large health systems in two states.
Funder: National Institute on Drug Abuse
Study End Date: 12/31/2023
The major goal of this project is to conduct a longitudinal cohort study to determine the effectiveness and safety of opioid tapering in three large health systems in two states.
Funder: National Institute on Drug Abuse
Study End Date: 12/31/2023
Investigator: Ingrid A. Binswanger, MD, MPH, MS
The purpose of this study is to use a prescription opioid registry containing EHR data across nine diverse health systems to assess how different lengths of buprenorphine retention are related to mortality.
Funder: National Institute on Drug Abuse
Study End Date: 05/31/2021
The purpose of this study is to use a prescription opioid registry containing EHR data across nine diverse health systems to assess how different lengths of buprenorphine retention are related to mortality.
Funder: National Institute on Drug Abuse
Study End Date: 05/31/2021
Investigator: Ingrid A. Binswanger, MD, MPH, MS
The goal of this study is to evaluate the effects of opioid prescribing policies on heroin overdose within a large health system.
Funder: Centers for Disease Control and Prevention
Study End Date: 08/31/2020
The goal of this study is to evaluate the effects of opioid prescribing policies on heroin overdose within a large health system.
Funder: Centers for Disease Control and Prevention
Study End Date: 08/31/2020